[Music]
[Music]
[Music]
[Applause]
what better way to
what better way to
what better way to
start this is my son Charlie he's 11
start this is my son Charlie he's 11
start this is my son Charlie he's 11
years
years
years
old and he's an hysterical quirky kid
old and he's an hysterical quirky kid
old and he's an hysterical quirky kid
he loves life and he proudly marches to
he loves life and he proudly marches to
he loves life and he proudly marches to
the beat of his own
the beat of his own
the beat of his own
drum he loves Kobe Bryant and Dr dre as
drum he loves Kobe Bryant and Dr dre as
drum he loves Kobe Bryant and Dr dre as
much as he loves writing risque mad libs
much as he loves writing risque mad libs
much as he loves writing risque mad libs
or preparing brisket paninis on his own
or preparing brisket paninis on his own
or preparing brisket paninis on his own
George Foreman girl
however when Charlie was three and a
however when Charlie was three and a
however when Charlie was three and a
half years old the dark fell from the
half years old the dark fell from the
half years old the dark fell from the
sky landed on my family and broke it
sky landed on my family and broke it
sky landed on my family and broke it
into more pieces than could ever be
into more pieces than could ever be
into more pieces than could ever be
imagined so many pieces in fact that
imagined so many pieces in fact that
imagined so many pieces in fact that
life as we knew it was
life as we knew it was
life as we knew it was
over you see my son Charlie was
over you see my son Charlie was
over you see my son Charlie was
diagnosed with duchen muscular distrophe
diagnosed with duchen muscular distrophe
diagnosed with duchen muscular distrophe
the most common and the most aggressive
the most common and the most aggressive
the most common and the most aggressive
form of duchen mus of
form of duchen mus of
form of duchen mus of
musculardrophe it's an infamous disease
musculardrophe it's an infamous disease
musculardrophe it's an infamous disease
in that it's the number one genetic
in that it's the number one genetic
in that it's the number one genetic
killer in the world of
killer in the world of
killer in the world of
children children that suffer from
children children that suffer from
children children that suffer from
duchen musculardrophe are missing a
duchen musculardrophe are missing a
duchen musculardrophe are missing a
protein in their body called distroofen
protein in their body called distroofen
protein in their body called distroofen
which is the largest protein in the body
which is the largest protein in the body
which is the largest protein in the body
and it's essential for muscle strength
and it's essential for muscle strength
and it's essential for muscle strength
and function an analogy that I often use
and function an analogy that I often use
and function an analogy that I often use
is it's like the steel cables of a
is it's like the steel cables of a
is it's like the steel cables of a
suspension bridge without the steel
suspension bridge without the steel
suspension bridge without the steel
cables the bridge is unable to withstand
cables the bridge is unable to withstand
cables the bridge is unable to withstand
any of mother nature's stresses kids
any of mother nature's stresses kids
any of mother nature's stresses kids
that are missing this very important
that are missing this very important
that are missing this very important
protein the muscles begin to deteriorate
protein the muscles begin to deteriorate
protein the muscles begin to deteriorate
even with simple activities as getting
even with simple activities as getting
even with simple activities as getting
up walking jumping uh for instance it
up walking jumping uh for instance it
up walking jumping uh for instance it
affects one in every 3,500
affects one in every 3,500
affects one in every 3,500
boys it's an equal opportunity disease
boys it's an equal opportunity disease
boys it's an equal opportunity disease
in that it knows no ethnic or geographic
in that it knows no ethnic or geographic
in that it knows no ethnic or geographic
boundaries doesn't matter what country
boundaries doesn't matter what country
boundaries doesn't matter what country
you're from doesn't matter what color
you're from doesn't matter what color
you're from doesn't matter what color
your skin is one in every 3,500 boys
your skin is one in every 3,500 boys
your skin is one in every 3,500 boys
throughout the world is born with this
throughout the world is born with this
throughout the world is born with this
disease the prognosis is horrifying it's
disease the prognosis is horrifying it's
disease the prognosis is horrifying it's
100%
100%
100%
fatal the disease is rapidly progressive
fatal the disease is rapidly progressive
fatal the disease is rapidly progressive
and affects every muscle in a kid's body
and affects every muscle in a kid's body
and affects every muscle in a kid's body
the their skeletal muscles the heart
the their skeletal muscles the heart
the their skeletal muscles the heart
which is a muscle and the muscles of
which is a muscle and the muscles of
which is a muscle and the muscles of
respiration
respiration
respiration
by adolescence the kids are wheelchair
by adolescence the kids are wheelchair
by adolescence the kids are wheelchair
bound and by their mid to late 20s they
bound and by their mid to late 20s they
bound and by their mid to late 20s they
die this is the type of news that
die this is the type of news that
die this is the type of news that
paralyzes
paralyzes
paralyzes
most the sadness the anger and the fear
most the sadness the anger and the fear
most the sadness the anger and the fear
is enough to stop anyone in their tracks
is enough to stop anyone in their tracks
is enough to stop anyone in their tracks
for my wife and I we were determined to
for my wife and I we were determined to
for my wife and I we were determined to
push through
this and to save our son's
this and to save our son's
this and to save our son's
life in just four months after we
life in just four months after we
life in just four months after we
received the tragic news that our son
received the tragic news that our son
received the tragic news that our son
was diagnosed with duchen musculardrophe
was diagnosed with duchen musculardrophe
was diagnosed with duchen musculardrophe
we decided to start Charlie's Fund a
we decided to start Charlie's Fund a
we decided to start Charlie's Fund a
nonprofit
nonprofit
nonprofit
organization that invests in
organization that invests in
organization that invests in
therapeutics
therapeutics
therapeutics
development for a therapy or a cure for
development for a therapy or a cure for
development for a therapy or a cure for
duchen
duchen
duchen
musculardrophe our mission is simple and
musculardrophe our mission is simple and
musculardrophe our mission is simple and
crucial and we have never wavered from
crucial and we have never wavered from
crucial and we have never wavered from
it from the first day we started our
it from the first day we started our
it from the first day we started our
foundation we raise money and we direct
foundation we raise money and we direct
foundation we raise money and we direct
it into the hands of those that we feel
it into the hands of those that we feel
it into the hands of those that we feel
have the best shot on goal developing a
have the best shot on goal developing a
have the best shot on goal developing a
therapy or a cure in time to save my son
therapy or a cure in time to save my son
therapy or a cure in time to save my son
Charlie's life and the tens of thousands
Charlie's life and the tens of thousands
Charlie's life and the tens of thousands
of boys who are needlessly suffering
of boys who are needlessly suffering
of boys who are needlessly suffering
from this disease just like
him we are in a race against time my
him we are in a race against time my
him we are in a race against time my
wife and I have been acutely aware of
wife and I have been acutely aware of
wife and I have been acutely aware of
this fact since day one and
this fact since day one and
this fact since day one and
unfortunately DMD was
unfortunately DMD was
unfortunately DMD was
winning and progress was simply not
winning and progress was simply not
winning and progress was simply not
moving fast enough for
moving fast enough for
moving fast enough for
us there were no drugs and there
us there were no drugs and there
us there were no drugs and there
currently are no drugs available for
currently are no drugs available for
currently are no drugs available for
these kids to take in order to slow the
these kids to take in order to slow the
these kids to take in order to slow the
progress of the disease with the
progress of the disease with the
progress of the disease with the
exception of steroids which does very
exception of steroids which does very
exception of steroids which does very
little to slow the
little to slow the
little to slow the
devastation and worse it's associated
devastation and worse it's associated
devastation and worse it's associated
with a host of terrible terrible side
with a host of terrible terrible side
with a host of terrible terrible side
effects so bad in fact that many
effects so bad in fact that many
effects so bad in fact that many
children are simply not able to take the
children are simply not able to take the
children are simply not able to take the
drug
itself we knew we had to do things
itself we knew we had to do things
itself we knew we had to do things
differently and we had to act
differently and we had to act
differently and we had to act
quickly one thing that was very apparent
quickly one thing that was very apparent
quickly one thing that was very apparent
to me was that we needed appropriate
to me was that we needed appropriate
to me was that we needed appropriate
level of focus to be devoted towards
level of focus to be devoted towards
level of focus to be devoted towards
this problem in order to make a
this problem in order to make a
this problem in order to make a
difference in time for Charlie at the
difference in time for Charlie at the
difference in time for Charlie at the
time we hired the world's only PhD level
time we hired the world's only PhD level
time we hired the world's only PhD level
uh scientist who devoted a 100% of his
uh scientist who devoted a 100% of his
uh scientist who devoted a 100% of his
efforts every single waking moment to
efforts every single waking moment to
efforts every single waking moment to
help us realize a therapy or a cure for
help us realize a therapy or a cure for
help us realize a therapy or a cure for
these boys it's amazing to think of
these boys it's amazing to think of
these boys it's amazing to think of
something so simple as just devoting
something so simple as just devoting
something so simple as just devoting
enough attention to a disease is what's
enough attention to a disease is what's
enough attention to a disease is what's
needed and yet no one had done it before
needed and yet no one had done it before
needed and yet no one had done it before
we did
we did
we did
it another thing that was acutely that
it another thing that was acutely that
it another thing that was acutely that
my wife and I were acutely aware of from
my wife and I were acutely aware of from
my wife and I were acutely aware of from
the beginning was a sense of urgency
the beginning was a sense of urgency
the beginning was a sense of urgency
time was not on our side the window of
time was not on our side the window of
time was not on our side the window of
opportunity was
opportunity was
opportunity was
narrow one of the annual meetings that
narrow one of the annual meetings that
narrow one of the annual meetings that
my wife and I and all the key opinion
my wife and I and all the key opinion
my wife and I and all the key opinion
leaders in the field for duchen
leaders in the field for duchen
leaders in the field for duchen
musculardrophe
musculardrophe
musculardrophe
uh one scientist uh was speaking and his
uh one scientist uh was speaking and his
uh one scientist uh was speaking and his
words have always stuck with me he got
words have always stuck with me he got
words have always stuck with me he got
up there and he spoke to an audience of
up there and he spoke to an audience of
up there and he spoke to an audience of
several hundred people and he
several hundred people and he
several hundred people and he
said "Myself included there are many
said "Myself included there are many
said "Myself included there are many
scientists in this room who can cure
scientists in this room who can cure
scientists in this room who can cure
duchen musculardrophe in a mouse it's
duchen musculardrophe in a mouse it's
duchen musculardrophe in a mouse it's
time we move these drugs out of the
time we move these drugs out of the
time we move these drugs out of the
animal models and into the kids before
animal models and into the kids before
animal models and into the kids before
another generation is needlessly lost."
another generation is needlessly lost."
another generation is needlessly lost."
I never forgot those words
I never forgot those words
I never forgot those words
that evening when I came home I said to
that evening when I came home I said to
that evening when I came home I said to
my wife I have an idea of what we're
my wife I have an idea of what we're
my wife I have an idea of what we're
going to
going to
going to
do we're going to screen every FDA
do we're going to screen every FDA
do we're going to screen every FDA
approved drug in the country for other
approved drug in the country for other
approved drug in the country for other
diseases and we're going to develop
diseases and we're going to develop
diseases and we're going to develop
tests to see if there's any of these
tests to see if there's any of these
tests to see if there's any of these
drugs that have any benefit in duchen
drugs that have any benefit in duchen
drugs that have any benefit in duchen
musculardrophe so we developed these
musculardrophe so we developed these
musculardrophe so we developed these
assays which are tests that are used to
assays which are tests that are used to
assays which are tests that are used to
screen uh thousands tens of thousands
screen uh thousands tens of thousands
screen uh thousands tens of thousands
sometimes millions of drugs in this case
sometimes millions of drugs in this case
sometimes millions of drugs in this case
there was a finite number of drugs
there was a finite number of drugs
there was a finite number of drugs
there's approximately 4,000 FDA approved
there's approximately 4,000 FDA approved
there's approximately 4,000 FDA approved
drugs for other
drugs for other
drugs for other
diseases just as I expected we got very
diseases just as I expected we got very
diseases just as I expected we got very
promising hits from that screen and then
promising hits from that screen and then
promising hits from that screen and then
we tested them in the animal model for
we tested them in the animal model for
we tested them in the animal model for
this disease some of which showed great
this disease some of which showed great
this disease some of which showed great
promise the results of this innovative
promise the results of this innovative
promise the results of this innovative
initiative two clinical trials one of
initiative two clinical trials one of
initiative two clinical trials one of
which is currently taking place at
which is currently taking place at
which is currently taking place at
John's Hopkins University the other is
John's Hopkins University the other is
John's Hopkins University the other is
taking place at Cincinnati Children's
taking place at Cincinnati Children's
taking place at Cincinnati Children's
Hospital both of which are working on
Hospital both of which are working on
Hospital both of which are working on
drugs that offer great promise in
drugs that offer great promise in
drugs that offer great promise in
improving the strength and function of
improving the strength and function of
improving the strength and function of
the skeletal muscles and the hearts of
the skeletal muscles and the hearts of
the skeletal muscles and the hearts of
these kids which means that there is
these kids which means that there is
these kids which means that there is
a good possibility that the quantity and
a good possibility that the quantity and
a good possibility that the quantity and
quality of these children's lives for
quality of these children's lives for
quality of these children's lives for
the first time in the history of this
the first time in the history of this
the first time in the history of this
disease is going to be marketkedly
disease is going to be marketkedly
disease is going to be marketkedly
improved
something else that we wanted to do that
something else that we wanted to do that
something else that we wanted to do that
was needed and that would distinguish
was needed and that would distinguish
was needed and that would distinguish
ourselves from the rest of the uh people
ourselves from the rest of the uh people
ourselves from the rest of the uh people
and experts that were devoted to doing
and experts that were devoted to doing
and experts that were devoted to doing
something about this disease was taking
something about this disease was taking
something about this disease was taking
risks thinking outside the box being
risks thinking outside the box being
risks thinking outside the box being
innovative in the early few months after
innovative in the early few months after
innovative in the early few months after
we started Charlie's fund I would
we started Charlie's fund I would
we started Charlie's fund I would
frantically scour the internet looking
frantically scour the internet looking
frantically scour the internet looking
for all of the most promising research
for all of the most promising research
for all of the most promising research
research that existed on this disease i
research that existed on this disease i
research that existed on this disease i
picked up the phone and I called every
picked up the phone and I called every
picked up the phone and I called every
scientist every clinician and every CEO
scientist every clinician and every CEO
scientist every clinician and every CEO
of a biotech company that was doing
of a biotech company that was doing
of a biotech company that was doing
anything that had to do with this
anything that had to do with this
anything that had to do with this
disease
disease
disease
within months I came up with a game plan
within months I came up with a game plan
within months I came up with a game plan
with the help of uh my adviserss what we
with the help of uh my adviserss what we
with the help of uh my adviserss what we
needed to do in this mining through the
needed to do in this mining through the
needed to do in this mining through the
uh uh multitude of possibilities i came
uh uh multitude of possibilities i came
uh uh multitude of possibilities i came
across this seedstage biotech company in
across this seedstage biotech company in
across this seedstage biotech company in
the
the
the
Netherlands they had less than 30 people
Netherlands they had less than 30 people
Netherlands they had less than 30 people
at the time and they were working on
at the time and they were working on
at the time and they were working on
proprietary technology that is something
proprietary technology that is something
proprietary technology that is something
from Star Trek it's a type of modified
from Star Trek it's a type of modified
from Star Trek it's a type of modified
gene therapy that tricks the muscles
gene therapy that tricks the muscles
gene therapy that tricks the muscles
into once again making the missing
into once again making the missing
into once again making the missing
protein I spoke of earlier called
protein I spoke of earlier called
protein I spoke of earlier called
distroofen although making it in a
distroofen although making it in a
distroofen although making it in a
shortened form with the hope that maybe
shortened form with the hope that maybe
shortened form with the hope that maybe
there's still enough function in this
there's still enough function in this
there's still enough function in this
protein that the kids quality of life
protein that the kids quality of life
protein that the kids quality of life
that the the speed at which this uh
that the the speed at which this uh
that the the speed at which this uh
muscle destruction was taking place
muscle destruction was taking place
muscle destruction was taking place
would slow
down we also did something that was out
down we also did something that was out
down we also did something that was out
of the box and innovative most
of the box and innovative most
of the box and innovative most
nonprofits when they're providing funds
nonprofits when they're providing funds
nonprofits when they're providing funds
or support for research do so in the
or support for research do so in the
or support for research do so in the
form of a gift or sponsored research
form of a gift or sponsored research
form of a gift or sponsored research
agreement where they roll out their
agreement where they roll out their
agreement where they roll out their
funding incrementally with milestone
funding incrementally with milestone
funding incrementally with milestone
achievement we decided to do something
achievement we decided to do something
achievement we decided to do something
bigger knowing that drug development is
bigger knowing that drug development is
bigger knowing that drug development is
expensive if these guys were on to
expensive if these guys were on to
expensive if these guys were on to
something exciting they were going to
something exciting they were going to
something exciting they were going to
need the money to demonstrate the proof
need the money to demonstrate the proof
need the money to demonstrate the proof
of concept so that enough value could be
of concept so that enough value could be
of concept so that enough value could be
built into this company that it would
built into this company that it would
built into this company that it would
turn the attention of big biotech and
turn the attention of big biotech and
turn the attention of big biotech and
big pharma the entities that have the
big pharma the entities that have the
big pharma the entities that have the
sufficient funds to take this promising
sufficient funds to take this promising
sufficient funds to take this promising
drug over the finish line we made an
drug over the finish line we made an
drug over the finish line we made an
equity investment of
equity investment of
equity investment of
$650,000 into this company the first
$650,000 into this company the first
$650,000 into this company the first
$650,000 we raised went into this
$650,000 we raised went into this
$650,000 we raised went into this
company
company
company
the result they're in a phase three
the result they're in a phase three
the result they're in a phase three
clinical trial in Europe in the United
clinical trial in Europe in the United
clinical trial in Europe in the United
States in Canada and Asia and currently
States in Canada and Asia and currently
States in Canada and Asia and currently
it is the most promising therapy in the
it is the most promising therapy in the
it is the most promising therapy in the
world for duchen musculardrophe
world for duchen musculardrophe
world for duchen musculardrophe
because of our support and others who
because of our support and others who
because of our support and others who
were willing to take a risk in this
were willing to take a risk in this
were willing to take a risk in this
company they have now recently uh
company they have now recently uh
company they have now recently uh
partnered with Glacos Smith Klein the
partnered with Glacos Smith Klein the
partnered with Glacos Smith Klein the
world's biggest pharmaceutical company
world's biggest pharmaceutical company
world's biggest pharmaceutical company
in the world for a deal potentially
in the world for a deal potentially
in the world for a deal potentially
worth over
worth over
worth over
$720
$720
$720
million with upfronts and milestone
million with upfronts and milestone
million with upfronts and milestone
achievements it's amazing what taking a
achievements it's amazing what taking a
achievements it's amazing what taking a
risk an educated risk if you will can
risk an educated risk if you will can
risk an educated risk if you will can
turn out if this company continues to be
turn out if this company continues to be
turn out if this company continues to be
successful then Charlie's fund will be
successful then Charlie's fund will be
successful then Charlie's fund will be
successful because of our equity
successful because of our equity
successful because of our equity
investment the return on our investment
investment the return on our investment
investment the return on our investment
will be used to refuel our efforts in
will be used to refuel our efforts in
will be used to refuel our efforts in
other promising therapeutic strategies
other promising therapeutic strategies
other promising therapeutic strategies
and I can once again place another
and I can once again place another
and I can once again place another
educated bet hopefully on the next uh
educated bet hopefully on the next uh
educated bet hopefully on the next uh
biotech company working on something for
biotech company working on something for
biotech company working on something for
our
our
our
children in summary our unprecedented
children in summary our unprecedented
children in summary our unprecedented
progress in a short time had less to do
progress in a short time had less to do
progress in a short time had less to do
about this groundbreaking scientific
about this groundbreaking scientific
about this groundbreaking scientific
discovery and more to do with having the
discovery and more to do with having the
discovery and more to do with having the
confidence and willingness to think
confidence and willingness to think
confidence and willingness to think
outside the box
outside the box
outside the box
on November
on November
on November
11th
11th
11th
1111 my son turned
11 this apicious numerological
11 this apicious numerological
11 this apicious numerological
phenomenon occurs literally once every
phenomenon occurs literally once every
phenomenon occurs literally once every
10,000
10,000
10,000
years it's amazing i remember on
years it's amazing i remember on
years it's amazing i remember on
Charlie's birthday I looked at my wife
Charlie's birthday I looked at my wife
Charlie's birthday I looked at my wife
Tracy and I said to her "This is the
Tracy and I said to her "This is the
Tracy and I said to her "This is the
year I'm going to deliver a devastating
year I'm going to deliver a devastating
year I'm going to deliver a devastating
blow to DMD." And I want to look back at
blow to DMD." And I want to look back at
blow to DMD." And I want to look back at
this year with no
this year with no
this year with no
regrets it's easy to lose focus when
regrets it's easy to lose focus when
regrets it's easy to lose focus when
you're doing something like we're trying
you're doing something like we're trying
you're doing something like we're trying
to accomplish at Charlie's Fun there's
to accomplish at Charlie's Fun there's
to accomplish at Charlie's Fun there's
so much at stake there are so many
so much at stake there are so many
so much at stake there are so many
possibilities there's no room for
possibilities there's no room for
possibilities there's no room for
error but moments like this are
error but moments like this are
error but moments like this are
important and it always goes back to our
important and it always goes back to our
important and it always goes back to our
mission and the one question are we
mission and the one question are we
mission and the one question are we
doing everything we can to move things
doing everything we can to move things
doing everything we can to move things
as fast as
as fast as
as fast as
possible halo
possible halo
possible halo
fugenone was a promising drug that I
fugenone was a promising drug that I
fugenone was a promising drug that I
remember reading in a respected
remember reading in a respected
remember reading in a respected
scientific journal that was being tested
scientific journal that was being tested
scientific journal that was being tested
in the animal model for duchen
in the animal model for duchen
in the animal model for duchen
musculardrophe a drug that was known to
musculardrophe a drug that was known to
musculardrophe a drug that was known to
venture capitalists and scientists for
venture capitalists and scientists for
venture capitalists and scientists for
other diseases that involved abnormal
other diseases that involved abnormal
other diseases that involved abnormal
fibrosis but the venture capitalists
fibrosis but the venture capitalists
fibrosis but the venture capitalists
lost faith after spending $80 million in
lost faith after spending $80 million in
lost faith after spending $80 million in
this drug but I knew that there was
this drug but I knew that there was
this drug but I knew that there was
still great promise in this drug for
still great promise in this drug for
still great promise in this drug for
duchen musculardrophe after speaking
duchen musculardrophe after speaking
duchen musculardrophe after speaking
with our scientific adviserss
with our scientific adviserss
with our scientific adviserss
the problem was I didn't have the tools
the problem was I didn't have the tools
the problem was I didn't have the tools
to figure out how to get the drug and
to figure out how to get the drug and
to figure out how to get the drug and
how to push it forward so that it could
how to push it forward so that it could
how to push it forward so that it could
potentially be given as a medicine to my
potentially be given as a medicine to my
potentially be given as a medicine to my
son and kids like
son and kids like
son and kids like
him i didn't turn my turn away from this
him i didn't turn my turn away from this
him i didn't turn my turn away from this
opportunity instead we once again
opportunity instead we once again
opportunity instead we once again
thought outside the box we decided to
thought outside the box we decided to
thought outside the box we decided to
recruit a team of drug development
recruit a team of drug development
recruit a team of drug development
experts people that represented the best
experts people that represented the best
experts people that represented the best
and brightest in big pharma and
and brightest in big pharma and
and brightest in big pharma and
biotech individuals with decades of
biotech individuals with decades of
biotech individuals with decades of
experience in making drugs
experience in making drugs
experience in making drugs
we did this in order to help us
we did this in order to help us
we did this in order to help us
negotiate deals with the biotech
negotiate deals with the biotech
negotiate deals with the biotech
companies to help us establish clinical
companies to help us establish clinical
companies to help us establish clinical
trial networks with the key opinion
trial networks with the key opinion
trial networks with the key opinion
leaders and the medical institutions
leaders and the medical institutions
leaders and the medical institutions
that would be conducting the trials and
that would be conducting the trials and
that would be conducting the trials and
to help us communicate with the
to help us communicate with the
to help us communicate with the
regulatory authorities which is
regulatory authorities which is
regulatory authorities which is
essential like the FDA in the United
essential like the FDA in the United
essential like the FDA in the United
States and the EMEA which is the
States and the EMEA which is the
States and the EMEA which is the
equivalent regulatory body in Europe
equivalent regulatory body in Europe
equivalent regulatory body in Europe
incredibly in less than one year what
incredibly in less than one year what
incredibly in less than one year what
have we accomplished with this team we
have we accomplished with this team we
have we accomplished with this team we
acquired that promising drug from that
acquired that promising drug from that
acquired that promising drug from that
dormant Israeli company and we started
dormant Israeli company and we started
dormant Israeli company and we started
believe it or not our own biotech
believe it or not our own biotech
believe it or not our own biotech
company called Halo Therapeutics in
company called Halo Therapeutics in
company called Halo Therapeutics in
order to accelerate the development of
order to accelerate the development of
order to accelerate the development of
this promising drug that we now call HT
this promising drug that we now call HT
this promising drug that we now call HT
100 and best of all we are on track and
100 and best of all we are on track and
100 and best of all we are on track and
expect to begin a clinical trial this
expect to begin a clinical trial this
expect to begin a clinical trial this
year
year
year
as a result of the great promise of this
as a result of the great promise of this
as a result of the great promise of this
drug and the expertise of the team that
drug and the expertise of the team that
drug and the expertise of the team that
I
I
I
assembled recently the United States and
assembled recently the United States and
assembled recently the United States and
the European Union has granted Halo
the European Union has granted Halo
the European Union has granted Halo
Therapeutics orphan drug
Therapeutics orphan drug
Therapeutics orphan drug
status this distinction provides us with
status this distinction provides us with
status this distinction provides us with
the regulatory and financial incentives
the regulatory and financial incentives
the regulatory and financial incentives
to significantly compress the time and
to significantly compress the time and
to significantly compress the time and
cost to get drugs into clinical trial
cost to get drugs into clinical trial
cost to get drugs into clinical trial
and the marketplace again focusing on
and the marketplace again focusing on
and the marketplace again focusing on
the
the
the
urgency because of our bold
urgency because of our bold
urgency because of our bold
efforts and the willingness and courage
efforts and the willingness and courage
efforts and the willingness and courage
to take matters into our own hands we
to take matters into our own hands we
to take matters into our own hands we
have now attracted the attention of the
have now attracted the attention of the
have now attracted the attention of the
biotech
biotech
biotech
industry in fact the Wall Street Journal
industry in fact the Wall Street Journal
industry in fact the Wall Street Journal
has recently written an article about
has recently written an article about
has recently written an article about
the groundbreaking innovation of
the groundbreaking innovation of
the groundbreaking innovation of
Charlie's fund and halo therapeutics in
Charlie's fund and halo therapeutics in
Charlie's fund and halo therapeutics in
the world of drug development and orphan
the world of drug development and orphan
the world of drug development and orphan
diseases
i'm a Harvard trained physician who has
i'm a Harvard trained physician who has
i'm a Harvard trained physician who has
an intimate understanding of the
an intimate understanding of the
an intimate understanding of the
language of genetic
language of genetic
language of genetic
medicine but my medical degree had
medicine but my medical degree had
medicine but my medical degree had
nothing to do with getting us to the
nothing to do with getting us to the
nothing to do with getting us to the
point of where we are right
point of where we are right
point of where we are right
now instead it's been focus relentless
now instead it's been focus relentless
now instead it's been focus relentless
determination and the courage to
determination and the courage to
determination and the courage to
innovate
although for us the motivation was the
although for us the motivation was the
although for us the motivation was the
need to save my son's life in
need to save my son's life in
need to save my son's life in
reality these principles can be applied
reality these principles can be applied
reality these principles can be applied
to any challenge that seemed to be
to any challenge that seemed to be
to any challenge that seemed to be
insurmountable and it's these same
insurmountable and it's these same
insurmountable and it's these same
principles that will help us rewrite the
principles that will help us rewrite the
principles that will help us rewrite the
medical textbooks for this murderous
medical textbooks for this murderous
medical textbooks for this murderous
disease and help us finally make duchen
disease and help us finally make duchen
disease and help us finally make duchen
history thank you
history thank you
history thank you
[Applause]